Stage 1 (primary Lyme disease)
  • Erythema migrans rash in 60 - 80% of people
  • Fever
  • Headache
  • Muscle aches (myalgias)
  • Joint aches (arthralgias)
  • Some patients have no symptoms

Stage 2 (secondary Lyme) - days to weeks after untreated primary Lyme

  • Multiple erythema migrans
  • Facial paralysis (bell's palsy), or other facial nerve problems
  • Meningitis
  • Heart block
  • Heart swelling (pericarditis, myocarditis)
  • Testicular swelling (Orchitis)
  • Liver swelling (hepatitis)
  • Eye swelling (iritis)

Stage 3 (tertiary Lyme) - months to years after untreated primary Lyme

  • Recurrent joint swelling (synovitis)
  • Recurrent tendonitis and bursitis
  • Mental and behavioral problems (psychotic behavior, memory loss, dementia, depression, sleep disorders)
  • Carpal tunnel syndrome and other nerve problems (peripheral neuropathies)

Even more problems reportedly associated with Lyme disease (Borrelia burgdorferi) infection. Please note, not all of these have been proven to be caused by this infection and may be due to other diseases.

Skin   
  • One or more erythema migrans rash
  • Lymphocytoma
  • Acrodermatitis chronica atrophicans
  • Heart   
  • Irregular beats
  • Heart block
  • Myocarditis
  • Chest pain
  • Vasculitis
     
  • Eyes   
  • Vision changes
  • Blindness
  • Retinal damage
  • Conjunctivitis
  • Eye swelling
  • Optic nerve atrophy
  • Nerves/Brain   
  • Severe Headache
  • Nerve conduction problems
  • Paralysis
  • Meningitis
  • Dizziness
  • Fainting
  • Double vision
  • Deviation of eyeball
  • Stroke
  • Seizures
  • Depression
  • Other behavioral changes
  • Gastrointestinal   
  • Nausea
  • Vomiting
  • Diarrhea
  • Anorexia
  • Loss of appetite
  • Liver function abnormalities
  • Tenderness and swelling of the Spleen
  • Lungs   
  • Difficulty breathing
  • Pneumonia
  • Pregnancy   
  • Miscarriage
  • Premature birth
  • Stillbirth
  • Congenital Lyme disease
  • Musculoskeletal   
  • Joint pain
  • TMJ
  •  

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